风湿

种植牙修复使干燥综合征患者的生活质量提高

作者:Almeida D, et al. 翻译:湖北省中医院熊丽桂 来源:中国风湿病公众论坛 日期:2018-06-14
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         种植牙修复使干燥综合征患者的生活质量提高

关键字:  干燥综合征 

        摘要:目的:干燥综合征是一种慢性自身免疫性疾病,它会累及腮腺继而影响口腔组织的健康。系统性回顾的目的是调查干燥综合征患者牙种植的存活率,牙种植体边缘骨丢失与生物学并发症的情况。材料与方法:入选标准包括前瞻性和回顾性队列研究、对照临床试验和随机临床试验(RCT)。在MEDLINE、Cochrane、科学网和丁香园上进行了一项一直持续到2017年6月,没有日期或语言限制的电子搜索。除此外,还进行了指南搜索和灰色文献检索。搜索过程、数据分析和质量评估由两位独立的评论作者完成。这个系统回顾的协议注册在PROSPERO系统的CRD42016053277下。

        结果:搜索和选择过程产生了6项研究,发表于1997至2016年间。平均随访期为3.97年,平均存活率为93.7%。研究报告显示牙种植体边缘骨丢失与生物学并发症发生的情况非常少。所有的研究观察到通过牙种植修复的受试者生活质量得以改善。

        结论:根据现有的数据及研究的局限性,结果显示干燥综合征患者种植牙的种植成活率高,牙种植体边缘骨丢失率低,生物并发症低。此外,所有纳入的研究都观察到通过牙种植修复的干燥综合征患者生活质量有提高。

        附原文:Abstract OBJECTIVES:The Sjögren's syndrome (SS) is a chronic autoimmune disease that affects salivation and consequently the health of oral tissues. The aim of this systematic review was to investigate the implant survival rate, marginal bone loss (MBL) and biological complications of dental implants in SS patients.MATERIALS AND METHODS:Eligibility criteria included prospective andretrospective cohort studies, controlled clinical trials, and randomized clinical trials (RCTs). An electronic search without date or language restrictions was carried out in MEDLINE, Cochrane, Web of Science, and LILACS until June 2017. In addition, manual search and in the grey literature were also conducted. The search process, data analysis, and quality assessment were performed by two independent reviewing authors. The protocol of this systematic review was registered in PROSPERO under number CRD42016053277.RESULTS:The search and selection process yielded 6 studies, published between 1997 and 2016. An average of 93.7% survival in a mean period of 3.97 years of follow-up was observed. A low number of MBL and biological complications were reported by the studies. All the studies analyzed observed an improvement in life quality of subjects with SS and rehabilitated through dental implants.CONCLUSIONS:With the limitations of this review and based on the available data, the dental implant therapy in SS patients seems to present high implant survival rate, low MBL and low biological complications. In addition, all included studies observed an increase in the quality of life of SS patients who were rehabilitated through dental implants.

        引自:Almeida D et al. Dental implants in Sjögren's syndrome patients: A systematic review. PLoS One. 2017 Dec 14;12(12):e0189507.

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